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  • Chemical Biology

    2520 Ninjago The golden Weapons Battle Arena 2 Minifigures Set Complete Lego oozwpk4262-LEGO Complete Sets & Packs

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    LEGO SUPER HEROES 76055 Killer Croc Sewer Smash Brand New & Sealed (Discontinued

    Here’s some medicinal chemistry combined with synthetic biology for you. Many people are used to thinking in terms of finding small-molecule probes for various cell targets, and those are valuable things. But what if you want to control a certain population of (for example) ion channels, but there aren’t any compounds that will do the… LEGO Marvel Super Heroes 76016 - Spider-Helicopter Rescue GREAT GIFT
  • Chemical News

    LEGO Heavy Duty Rescue Helicopter Construction Toy

    LEGO MARVEL Guardians of the Galaxy Milano Spaceship Rescue (76021) New But Open I was interested to see this paper, which goes into detail on a chemical phenomenon that many have seen but no one understands very well: triboluminescence. That word meets with a blank stare or instant recognition; there’s not much in between. It means “emission of light when a material is physically broken”, and that encompasses… LEGO Batman Movie 70907 Killer Croc Tail-Gator - Brand New
  • Analytical Chemistry

  • Cancer

  • Drug Assays

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    LEGO 7627 Indiana Jones Kingdom Temple of the Crystal Skull New damaged Boxset A common question – well, it should be a common question, anyway – is “How do I make sure that this compound collection is a useful one to screen?” There are alternative forms that come down to the same issues – if you’re putting together a new focused screening set, what should be in it?… Read More
  • Biological News

    LEGO Hero Factory 6201 Toxic Reapa

    A scientific giant, Sydney Brenner has died at the age of 92. He was present at the beginning of molecular biology – while in the chemistry department at Oxford, he car-pooled with Dorothy Hodgkin, Leslie Orgel, Jack Dunitz and others over to Cambridge to see Watson and Crick’s new model for the structure of DNA… LEGO Technic 42033 Record Breaker Set
  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

  • Academia (vs. Industry)

    Startup Culture, Starting

    LEGO DC Comics Super Heroes 76087 Justice League Flying Fox Batmobile... Many readers of this blog work in the biopharma industry, naturally, and of those, many are in and around the (few) locations where a great many of the companies in the industry are born. I myself am in the Boston/Cambridge area, famously thick with companies large and small, and then you have the Bay area… LEGO STAR WARS - 75150 Vader's TIE Advanced Vs. A-Wing Brand New In Sealed Box
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